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The Various Types Of Stem Cell Therapy Indiana Residents May Wish To Know

By Maryellen Lamb


There are a number of things regarding stem cell therapy Indiana residents should know as they consider undergoing this modality of treatment. In this technique, adult progenitor cells that have not differentiated are used to replace those that have been damaged by disease or injury. The cells used to achieve this are described as being pleuripotential. This means that they can differentiate into almost any type of specialised tissue.

Most of the cells in the adult human being have specialised to perform various functions. For instance cardiac cells are adapted to contract as they pump blood and to conduct electrical impulses, cells of the alimentary canal have features that facilitate digestion of food, neurons and oligodendrocytes that make up brain tissue are specialised to transmit nerve impulses and so on. Once a cell is specialised to perform a certain function, it cannot perform any other.

When cells are damaged due to injury or disease the innate reparative mechanisms in the body attempt to replace them. Unfortunately, this is not always effective and may lead serious functional deficits. For this reason, there is need to augment this process to speed up the process as well as make it more effective. Stem cell treatment ensures that the affected cells, tissues or organs regain as much of their initial function as possible.

Although the treatment is largely still in the experimental phase for most conditions, there are a few areas where there has been a breakthrough. One of these areas is the use of bone marrow transplants. A normal bone marrow contains precursor cells that differentiate over time to produce the different components that make up whole blood. Should there be a deficiency in any of these components it is possible to replenish them using precursors from the marrow.

Bone marrow transplant has become particularly useful for patients suffering from the adverse effects of cancer treatment. Cancer therapy typically comprises chemotherapy, radiotherapy and surgery. Chemotherapy and radiotherapy have low selectivity and often end up damaging normal tissues when they are administered to patients. After every cycle of treatment, patients may receive some bone marrow components to help replace the damaged cells.

Apart from bone marrow cells, the therapy is also achieved using foetal stem cells. These are undifferentiated cells that have been obtained from a human foetus. The cells are usually injected directly into the affected tissue or organ where they start to divide and differentiate. Factors known as cytokines are added to help speed up the process.

The diseases that have benefited from stem cell therapy include cancer, cardiac disease, diabetes mellitus, stroke, Parkinson disease, muscle damage and Celiac disease among others. The heart and the brain are arguably the most important organs in the body yet the most susceptible to injury. This is because the two are made of cells that have differentiated permanently but have no mechanism for replacement. The therapy has, for this reason, been a great step as regards the treatment of stroke and myocardial infarcts.

The therapy has spread rapidly from its origin in Europe and is now available in almost any part of the world. An important thing about stem cell therapy Indiana residents should know is that results are variable. Success is determined by patient age, severity of disease, and co-existing diseases. Luckily, the majority of patients respond very well.




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